This is my rather depressing take on the Fermi Paradox.
There is no point in anything.
We humans are programmed/evolved to make sense out of the environment, so we find it hard to accept that large complex artefacts, like the universe for example, are pointless. This has allowed us to confabulate higher meanings that keep us going.
But if a truly rational being accepts that there is no creator/mysticism/purpose then what is the point?
Evolution generates its own purpose; survival. But a rational being will not be able to deceive itself for long if the universe really is devoid of higher purpose.
These minds will euthanize leaving nothing behind.
This may be a view in common circulation. Ian M Banks touches on the idea in one of his books when he describes a clean AI free of any of the “noise” of the creating species. These AIs always sublime immediately.